Infection associated with immunosuppressive therapy.

sarcoma' refers to a miscellaneous group of undifferentiated tumours which may represent rather different malignant diseases. An increased incidence of lymphomas has also been observed in three congenital immunological deficiency diseases, namely, ataxia-telangiectasia, the Wiscott-Aldrich and Chediak-Higashi syndromes (Table 4). The evidence that malignant disease is increased in patients who are immunosuppressed must be viewed with a certain amount of circumspection. The malignant diseases described have usually involved the lymphoreticular system and this is affected directly by the cytotoxic immunosuppressive treatment and in the congenital abnormalities of this system.